Success rate of in vitro fertilization
Release time : 06/13/2025 09:30:02
With the advancement of science and technology, in-vitro fertilization (IVF) has become increasingly popular. Its maturity has also brought benefits to many families, leading to an increasing number of families considering having IVF to create new life.
But how high is the success rate of IVF? This article will introduce you to the success rate, process, and differences between IVF and intrauterine insemination (IUI). IVF Success Rate: The success rate of IVF varies among individuals, typically ranging from 30% to 40%. This means that out of every 100 attempts made with IVF, approximately 30 to 40 women eventually succeed in pregnancy. However, as age increases, the success rate may decrease. For example, the success rate for women over 35 years old may drop below 20%. IVF Process: IVF is a reproductive technology that assists couples who cannot conceive naturally. Here's a basic outline of the IVF process: 1. Ovulation induction: The doctor administers ovulation-inducing medication to stimulate multiple eggs from the patient's ovaries. 2. Egg collection: Under ultrasound guidance or laparoscopic surgery, the doctor retrieves mature eggs from the ovaries. 3. Sperm processing: The patient's sperm are processed in the laboratory to improve their fertilization ability. 4. Fertilization: The processed sperm are combined with the egg to form an embryo. 5. Embryo transfer: The embryo is implanted into the patient's uterus, usually several days after ovulation. 6. Pregnancy monitoring: After the embryo implantation, the doctor regularly checks the patient's health status to ensure the embryo's healthy development. Differences Between IVF and IUI: 1. Purpose: IVF is mainly used for treating infertility in men, while IUI is primarily used for female infertility. 2. Process: IVF involves in vitro fertilization and embryo culture, while IUI involves directly introducing sperm into the woman's uterus. 3. Success Rate: Since IVF involves in vitro fertilization and embryo culture, its success rate is generally higher than that of IUI. 4. Cost: IVF costs are usually higher due to the complex technology and equipment involved. IUI costs are relatively lower. In summary, both IVF and IUI are assisted reproductive technologies, but they differ in purpose and method. The choice of which technique to use depends on the couple's individual situation and needs.
In vitro fertilization (IVF) success rate, medical technology is developing rapidly, and more and more families are considering IVF to create a new life.
So, how high is the success rate for in vitro fertilization? Let's look at a professional analysis.
The success rate of IVF-ET treatment is generally assessed by the clinical pregnancy rate, which refers to the proportion of embryo transfer cycles in which a gestational sac is observed by vaginal ultrasound at 28-30 days post-embryo transfer.
The success rates of different IVF centers vary. The average success rate per transfer cycle in most centers is 30% to 50%, while some centers report a success rate of 60% to 70% per transfer cycle. The clinical treatment success rate is influenced by various factors, such as patient selection, clinical treatment methods, and laboratory techniques.
There are many factors that affect the success of IVF, including female age, causes of infertility, and the quality of laboratory testing at IVF centers.
1. Age is a crucial factor affecting the success rate of IVF, as with age increasing, there is a reduction in the number of ovarian eggs, their quality decreases, the fertilization rate drops, and the pregnancy rate significantly decreases, while the miscarriage rate increases.
41-42 year old women, the pregnancy rate of IVF is 12%; the live birth rate per embryo transfer for women over 42 years old is only 5.9%; the abortion rate for women over 43 years old is 50%.
2. Ovarian cysts significantly reduce the implantation rate and pregnancy rate, reducing the pregnancy rate by 50%.
Therefore, women with hydrosalpinx should have the hydrosalpinx removed prior to IVF.
3. Abnormal uterine conditions such as endometrial polyps, endometritis, and prior surgery or inflammation (tuberculosis is the most common) can affect embryo implantation.
The process of IVF involves the following six steps: 1. Ovulation induction treatment: Since not every egg can be fertilized and not every fertilized egg can develop into a viable embryo, it is necessary to obtain multiple eggs from a woman in order to ensure that there are embryos available for transfer. This requires ovulation induction treatment for the woman.
2. Under B-ultrasound guidance, the egg retrieval physician uses a special needle to puncture mature follicles through the vagina and extract the eggs.
Oocytes are typically retrieved under intravenous anesthesia, so women do not feel the pain of the procedure.
3. Extraction of sperm for in vitro fertilization: When the female undergoes oocyte retrieval, the male performs ejaculation.
After special washing process, the semen is put into special medium and then natural combination is expected.
This is the so-called routine fertilization method.
4. After fertilization, a very thin embryo transfer catheter is used to insert the best embryos into the mother's uterus through the cervix. The number of embryos to be transferred is determined based on age, embryo quality, and previous outcomes of IVF treatment, typically involving the transfer of 2 to 3 embryos.
In recent years, to reduce the rate of multiple pregnancies, some centers have opted for single embryo transfer or maximum of two embryos.
Since the embryo transfer catheter is very thin and the doctor moves it gently, patients usually have no pain.
5. Luteal Phase Support: Due to the use of GnRH agonists/antagonists and ovulation-inducing agents, as well as the loss of follicular granulosa cells resulting from oocyte retrieval, women often experience insufficient luteal function during their oocyte retrieval cycle. They require the administration of progesterone and/or human chorionic gonadotropin (hCG) for luteal phase supplementation or support.
If there is no pregnancy, discontinue the administration of progesterone and await menstruation.
If pregnancy occurs, continue the use of progesterone until 3 weeks after the first fetal heartbeat is seen on B-scan.
6. The determination of pregnancy is made by measuring serum hCG 14 days after embryo transfer to confirm pregnancy.
At 21 days after embryo transfer, the serum hCG is measured again to assess the development of the embryo.
30 days after embryo transfer, an intrauterine pregnancy is diagnosed by transvaginal ultrasound examination to confirm the presence of a gestational sac and fetal heartbeat.
How much does in vitro fertilization (IVF) cost? The initial expense for IVF is primarily due to the cost of ovulation induction medication. Since the cost of these medications is high, and the external conditions required for egg fertilization and embryo development are demanding, the cost of one case of IVF is also relatively high.
Therefore, couples seeking in vitro fertilization must consider not only their own conditions but also their financial capabilities and the determination to have a baby.
Due to the varying dosages of medication used by each patient, the costs for fertility treatment vary accordingly. Generally speaking, younger patients with better ovarian responses have a higher success rate and thus require a lower cost.
Due to the differences in imported and domestic drugs, there can be a significant difference in costs.
Secondly, there are several treatment cycles for in vitro fertilization, and the cost varies for each cycle. Additionally, there is a charge associated with pre-treatment examinations.
The specific amount of fees varies from place to place.
Therefore, before undergoing in vitro fertilization, it is important to inquire about the specific costs and choose accordingly based on your financial circumstances.
Moreover, even if in vitro fertilization is successful, there will be subsequent expenses, which are the costs associated with the later stages of treatment.
The length of treatment is a factor here. The sooner it's successful, the lower the total cost.
Therefore, before determining the specific cost, it is essential to first estimate the success rate to predict the approximate expenses.
Opt for hospitals with a high success rate and relatively lower costs.
Finally, for couples from other places, travel and accommodation should be included in the cost. Treatments that take a long time are also more expensive in this regard.
Therefore, opting for a hospital located near oneself can reduce costs, but it is essential to ensure the success rate of IVF.
The low success rate, the costs incurred and the harm to one's own body are far greater than the cost of renting a place.
The lower the hospital's level, the longer the treatment cycle, with each increase in the treatment cycle, the lower the success rate of subsequent pregnancies, and hence the cost will rise again.
Hence, we should choose carefully and handle it with caution.
The difference between IVF and ICSI is not clear to many couples considering ways to welcome a baby, and they are not quite sure of the difference between IVF and ICSI.
Let me explain to everyone the difference between in vitro fertilization and artificial insemination.
In vitro fertilization (IVF) is a reproductive assisted technique that involves the manipulation of sperm, eggs, and embryos in vitro before transferring them into the human body to help couples with infertility conceive. This process includes techniques such as intrauterine insemination, ovum transfer, and in vitro fertilization with embryo transfer. The pregnancy process following IVF is identical to that of regular pregnancies.
To undergo in vitro fertilization (IVF), one must be either both fallopian tubes are blocked or the pelvic environment is unfavorable.
Because the fallopian tubes are the channels for the union of sperm and egg, their failure to open can lead to the inability of sperm and egg to meet. This only occurs if the female's egg is removed and the male's sperm is taken out, then they are combined in vitro. In fact, in vitro fertilization is essentially a process of combining sperm and egg. However, once the sperm and egg are combined, the formation of a fertilized egg begins. The first day, when the two cells are placed together, the second day sees them as a double cell, and by the third day, it has become a four-cell stage, growing at a multiple rate. Typically, by the eighth cell stage, they are implanted into the uterus. Therefore, the success rate of IVF depends on various factors. It includes the quality of the female's eggs and the quality of their thawing, the quality of the sperm-egg combination, and the environment of the uterus after implantation.
In vitro fertilization is a method of artificial insemination where the male semen is injected into the female reproductive tract to assist conception. It is primarily used for male infertility.
In vitro fertilization (IVF) is divided into two types: intra-uterine insemination with a partner and intra-uterine insemination without a partner.
Who is suitable for artificial insemination? At a minimum, one must have a patent ovarian follicle and the condition of the patent fallopian tubes must be favorable for ovulation. In actuality, artificial insemination involves the selective injection of sperm into the uterine cavity after ultrasound-guided ovulation has occurred. However, this procedure requires the fallopian tube's fimbria to naturally capture the egg, ensuring that it can reach the fallopian tube where it may encounter the sperm. If the conditions of the fallopian tubes are poor, the fertilization cannot occur.
It is evident that the differences between in vitro fertilization and artificial insemination are quite significant.
The medical information provided in this text is for reference only and should not be used for any medical diagnosis or treatment.
In case of discomfort, it is advised to seek medical attention immediately. For accurate diagnosis and treatment, please consult a professional in person.