The role of Mediterranean anemia examination in pregnant women
Release time : 05/08/2025 09:30:02
Giant Cell Arteritis, a hereditary disease, can be treated with symptomatic treatment. If it is mild, there is no need for extensive treatment; it can be managed by paying attention to daily activities.
If it is serious, then we need to consider the genetic rate of the next generation. We should make a good choice for our baby.
Many individuals overlook the examination for thalassemia during premarital or prenatal check-ups. In fact, this examination is essential and has certain benefits.
Pregnant women with thalassemia undergoing examinations, in fact, are all about understanding their physical condition better and making the best choices.
Therefore, the examination for thalassemia in pregnant women is also the same; this allows parents to prepare themselves mentally to welcome their baby. It might be healthy, or there is a 25% chance of carrying thalassemia. This examination fully demonstrates its role.
Generally speaking, if both spouses of a couple are carriers of the same type of thalassemia gene, their offspring have a 25% chance to be normal, a 50% chance to be carriers, and a 25% chance to be patients with severe thalassemia.
To effectively prevent this disease, blood samples are required for peptide chain testing and genetic analysis.
The mental and economic burdens placed on families by children with severe anemia are unbearable.
Severe α-thalassemia often results in fetal stillbirth or death shortly after birth.
Heavy-chain beta thalassemia is more severe. Infants with this condition typically develop symptoms within three to six months after birth, requiring long-term blood transfusions and the injection of iron-removing medications. These treatments are expensive, and children often die from the accumulation of excess iron due to prolonged blood transfusions. The psychological and financial burdens associated with these issues are also far-reaching.
Pregnant women with thalassemia are common types of anemia, and it is highly hereditary. So, have you guys prepared for the check-up? Have you done your research? What tests does this examination involve? The examination for thalassemia in pregnant women is not just about the mother; if there's anything abnormal, the father should also cooperate. When examining thalassemia, it is often combined with family genetic history. If the family does not carry the gene for thalassemia, they cannot be diagnosed with this disease.
If both parents have thalassemia, then the probability of having the disease in the offspring is 75%.
If one parent has thalassemia, the probability of having thalassemia in a child is 50%.
Therefore, anyone in the family with a thalassemia patient must be checked.
Thalassemia can be detected by routine blood tests or bone marrow examination, combined with family history.
Pulmonary anemia, common anemia, infectious hepatitis, and liver cirrhosis should be distinguished from one another.
Mild地中海贫血 and iron deficiency anemia have very similar clinical manifestations and are often misdiagnosed. Patients with thalassemia may also present with symptoms such as jaundice and splenomegaly, which can be mistaken for cirrhosis or infectious hepatitis during examinations. However, further investigation will reveal the true diagnosis.
Therefore, initial blood tests are analyzed in light of the situation. If abnormalities are detected, peptide chain testing and gene analysis are required.
Pregnant women may also need to undergo sheep wool pricking.
Gallery of Pregnant Women with地中海贫血: Many first-time pregnant mothers may not know when to undergo certain tests! Generally, the time for screening for G6PD deficiency in pregnant women is during the first prenatal checkup. Before or early in pregnancy, through genetic testing, the abnormal loci of α and β globin genes can be identified, preparing for prenatal diagnosis.
If the father-to-be has not undergone marriage counseling or genetic testing for thalassemia or other genetic disorders, he must also participate in the first prenatal examination for blood tests.
At 11-14 weeks of gestation, approximately 2-5g of chorionic villus tissue is taken for genetic testing to determine the presence or absence of α or β thalassemia genes in the fetus. This method effectively prevents the birth of hemolytic anemia or malformed infants with severe thalassemia.
During the screening for thalassemia, blood tests are conducted to check the complete blood count. Pregnant women should undergo a detailed examination to ensure the birth of healthy babies.
Analysis of Maternal Mediterranean Anemia Test Results: During a routine maternal screening for thalassemia, the blood tests are usually conducted to screen for thalassemia. If there is an abnormal result, further testing such as hemoglobin electrophoresis, protein chain analysis, and genetic analysis of thalassemia genes are required to confirm the diagnosis of thalassemia.
Many people are stunned by the results of these examinations and are unsure about what is normal and what is risky. Although doctors will provide explanations, without some preparation, how can one grasp their various statements? The reference table for the normal values of the pregnant woman's thalassemia trait: Analysis of the pregnancy-related thalassemia examination results is as follows: 1. Routine blood tests primarily examine the mean corpuscular volume (MCV) and mean corpuscular hemoglobin content (MCH), with all types of thalassemia exhibiting reduced MCV or MCH, but gene carriers of the static type may be normal.
Hemoglobin levels can be reduced in patients with severe, intermediate and mild anemia.
This can only indicate the risk of iron deficiency anemia and cannot serve as diagnostic criteria.
2. Hemoglobin electrophoresis is used to diagnose abnormal hemoglobins, including severe and intermediate microangiopathic anemias, for definitive diagnosis.
An elevated HbA2 level is the most significant diagnostic indicator for mild beta-thalassemia.
In iron-deficiency anemia, HbA2 is often reduced, which can be used to differentiate from mild beta-thalassemia.
3. Peptide chain detection is mainly used clinically for the diagnosis of mild α-thalassemia.
Normally negative, positive for peptide chain can diagnose mild α-thalassemia.
Gene analysis can replace all the aforementioned tests, but it is difficult to conduct due to the high requirements for equipment, laboratory facilities, and technical personnel. Generally, hospitals find it challenging to carry out these tests, and the cost of the test is quite high.
In cases where both spouses are of the same type of thalassemia trait, close prenatal diagnosis is required.
If the results indicate normal or mild anemia, there is no significant impact on the fetus and you can proceed with childbirth.
In the case of a severe condition, it is advised to promptly induce labor to prevent physical and psychological harm to the pregnant woman.
Is it necessary for pregnant women with thalassemia to undergo an examination? Some expectant mothers do not attach great importance to the examination of thalassemia, thinking that whether it is conducted or not does not matter. In fact, this examination is very necessary.
Screening for thalassemia in pregnant women is conducted through standard prenatal blood tests.
If the average red blood cell volume of pregnant women is less than 80, they may be carriers of the thalassemia gene. In this case, their spouse also needs to undergo an average red blood cell volume check. If the spouse's average red blood cell volume is greater than 80, there is no concern about having a child with thalassemia.
If the average red blood cell volume of the spouse is less than 80, both must be diagnosed for confirmation to determine if they are carriers of the same thalassemia gene. If both are carriers, further testing with chorionic villus sampling or amniocentesis must be performed to diagnose the fetus as a gene carrier.
Moreover, since marital anemia in pregnant women is a genetic issue, it is crucial for expectant mothers to undergo timely screening. Otherwise, it may significantly impact their future life. Therefore, this examination aligns with the concept of promoting healthy births and preserving family health, thus recommending that marital anemia be screened.
The cost of a pregnancy-related beta thalassemia screening is determined by the local circumstances or the specifics of the hospital where the screening is conducted, not a fixed amount. However, based on general data provided by Mambo, we can provide an approximate cost to serve as a reference for everyone! Generally, during beta thalassemia screening, a routine complete blood count (CBC) is performed first, costing about 20-30 yuan.
If abnormal results are found in routine blood tests, further examinations such as beta-thalassemia gene analysis should be conducted. The cost of a thalassemia gene test generally ranges between 250-300 yuan, with the total cost ranging from 500-1000 yuan.
Therefore, the cost of a地中海贫血 test depends on the number of tests required during the examination process.
This is merely a reference price, and the actual charges will vary depending on the region and the nature of the hospital. For those in need, it's best to consult the relevant local hospital for more information.
The medical content in this text is for reference only.
In the event of discomfort, it is recommended to seek medical attention immediately. Consultations and diagnoses are conducted in person by qualified medical professionals.